Beatrice (Valeria Bruni-Tedeschi) is a motor-mouthed fantasist, a self-styled billionaire countess who believes she's on intimate terms with world leaders. Donatella (Micaela Ramazzotti) is a tattooed introvert, a fragile young woman locked in her painful past. Both women are patients at the Villa Biondi, a progressive psychiatric clinic in the Tuscan hills. Paolo Virzì tells the story of the unpredictable and moving friendship that develops between the two women as they flee the clinic.